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According to the Telegraph, Dan Robson is set to make the cut ahead of Danny Care while the same report suggests Chris Robshaw will also be left out.
The 32 year-old, who has 66 caps, is expected to return to Harlequins in the Premiership Cup against Saracens on Jan 26 and is likely to come into contention for selection later in the Six
Nations once he has proven his fitness.
Danny Cipriani, who has just returned to action for Gloucester after sustaining a chest injury in December, is also expected to miss out.
Jonathan Joseph is also set to be overlooked, despite being set to return from a long injury lay-off this weekend.
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