New drug blocks brain metastasis


Play all audios:

Access through your institution Buy or subscribe Silibinin blocks brain metastasis in humans and mice, according to a new study published in _Nature Medicine_. Investigators found that


silibinin stops reactive astrocytes from making the brain microenvironment amenable to tumour growth. Brain metastasis is a common complication in patients with systemic cancer and is


associated with a poor prognosis. Surgery and radiotherapy are the only treatments currently available for the majority of individuals with brain metastases and novel approaches are sorely


needed. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Access Nature and 54 other Nature Portfolio journals Get


Nature+, our best-value online-access subscription $29.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 12 print issues and online access $209.00 per year only


$17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout


ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES ORIGINAL ARTICLE * Priego, N. et al. STAT3 labels a


subpopulation of reactive astrocytes required for brain metastasis. _Nat. Med._ https://doi.org/10.1038/s41591-018-0044-4 (2018) Article  Google Scholar  Download references AUTHOR


INFORMATION AUTHORS AND AFFILIATIONS * Nature Reviews Neurology http://www.nature.com/nrneurol/ Charlotte Ridler Authors * Charlotte Ridler View author publications You can also search for


this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Charlotte Ridler. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Ridler, C.


New drug blocks brain metastasis. _Nat Rev Neurol_ 14, 452 (2018). https://doi.org/10.1038/s41582-018-0037-4 Download citation * Published: 25 June 2018 * Issue Date: August 2018 * DOI:


https://doi.org/10.1038/s41582-018-0037-4 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not


currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative