Glycolysis and ar expression as biomarkers


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Access through your institution Buy or subscribe Assessing androgen receptor (AR) expression and glycolytic activity using PET–CT imaging could be useful for predicting the prognosis of


patients with metastatic castration-resistant prostate cancer (CRPC), say researchers. Josef Fox and co-workers enrolled 133 patients with progressive metastatic CRPC to undergo dual PET–CT


imaging using 18F-fluorodeoxyglucose (18F-FDG) as an indicator of tumour glycolysis and 18F-fluorodihydrotestosterone (18F-FDHT) as an indicator of AR expression. This is a preview of


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* Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Fox, J. J. _ et al_. Positron emission tomography/computed tomography–based


assessments of androgen receptor expression and glycolytic activity as a prognostic biomarker for metastatic castration-resistant prostate cancer. _JAMA Oncol._


http://dx.doi.org/10.1001/jamaoncol.2017.3588 (2017) Download references Authors * Rebecca Kelsey View author publications You can also search for this author inPubMed Google Scholar RIGHTS


AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kelsey, R. Glycolysis and AR expression as biomarkers. _Nat Rev Urol_ 15, 2 (2018).


https://doi.org/10.1038/nrurol.2017.205 Download citation * Published: 28 November 2017 * Issue Date: January 2018 * DOI: https://doi.org/10.1038/nrurol.2017.205 SHARE THIS ARTICLE Anyone


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