Renoprotective effects of glp1r agonists and sglt2 inhibitors


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New data from the LEADER trial show that the glucagon-like peptide 1 receptor agonist liraglutide protects against diabetic nephropathy in patients with type 2 diabetes mellitus. The


renoprotective efficacy of liraglutide is not, however, as great as that reported for the sodium-glucose cotransporter 2 inhibitor emplagiflozin in the EMPA-REG OUTCOME trial. Access through


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Read our FAQs * Contact customer support REFERENCES * Muskiet, M. H. _ et al_. GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes. _Nat. Rev. Nephrol._ 13,


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Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal


University, Changsha, 410013, China Berthold Hocher * Institute of Nutritional Science, University of Potsdam, 14558, Nuthetal-Potsdam, Germany Oleg Tsuprykov Authors * Berthold Hocher View


author publications You can also search for this author inPubMed Google Scholar * Oleg Tsuprykov View author publications You can also search for this author inPubMed Google Scholar


CORRESPONDING AUTHOR Correspondence to Berthold Hocher. ETHICS DECLARATIONS COMPETING INTERESTS B.H. is a consultant for Boehringer Ingelheim on the development of dipeptidyl peptidase 4


(DPP4) inhibitors and has received research funding from this company for investigation of the renal effects of the DPP4 inhibitor linagliptin. O.T. declares no competing interests.


POWERPOINT SLIDES POWERPOINT SLIDE FOR TABLE 1 RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Hocher, B., Tsuprykov, O. Renoprotective effects of GLP1R


agonists and SGLT2 inhibitors. _Nat Rev Nephrol_ 13, 728–730 (2017). https://doi.org/10.1038/nrneph.2017.140 Download citation * Published: 09 October 2017 * Issue Date: December 2017 * DOI:


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