Opening the gateway to tumors | Nature Medicine

T cells can turn back cancer, but they don't always reach tumor cells in sufficient numbers to do so. A close look at the cells of tumor blood vessels suggests a way to boost T cell

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institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Buckanvich, R.J. et al. _Nat. Med._ 14, 28–36 (2008). Article  Google Scholar  * Galon, J. et al.

_Science_ 313, 1960–1964 (2006). Article  CAS  Google Scholar  * Zhang, L. et al. _N. Engl. J. Med._ 348, 203–213 (2003). Article  CAS  Google Scholar  * Coussens, L.M. & Werb, Z.

_Nature_ 420, 860–867 (2002). Article  CAS  Google Scholar  * Nelson, J. et al. _Nat. Rev. Cancer_ 3, 110–116 (2003). Article  CAS  Google Scholar  * Kubes, P., Suzuki, M. & Granger,

D.N. _Proc. Natl. Acad. Sci. USA_ 88, 4651–4655 (1991). Article  CAS  Google Scholar  * Monsurro, V. et al. _J. Immunol._ 166, 5817–5825 (2001). Article  CAS  Google Scholar  * Morgan, R.A.

et al. _Science_ 314, 126–129 (2006). Article  CAS  Google Scholar  * Rosenberg, S.A., Yang, J.C. & Restifo, N.P. _Nat. Med._ 10, 909–915 (2004). Article  CAS  Google Scholar  * Kirkby,

N.S., Hadoke, P.W., Bagnall, A.J. & Webb, D.J. _Br. J. Pharmacol._ published online, doi:10.1038/sj.bjp.0707516 (29 October 2007). Download references AUTHOR INFORMATION AUTHORS AND

AFFILIATIONS * Michael H. Kershaw is in the Cancer Immunology Research Program, Peter MacCallum Cancer Centre, St. Andrews Place, Melbourne, Victoria 3002, Australia.

[email protected], Michael H Kershaw Authors * Michael H Kershaw View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS

Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kershaw, M. Opening the gateway to tumors. _Nat Med_ 14, 13–14 (2008). https://doi.org/10.1038/nm0108-13 Download citation *

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