Vascularization of skin grafts

ABSTRACT THE question of how skin grafts are revascularized is still not resolved1–3. In particular, it is not known whether the vessels in the vascular bed of a graft derive from the host

or the donor. In what follows, we provide three independent lines of evidence which suggest that in full-thickness skin grafts, the vessels are native to the graft at least for the first

several days and during the period of allograft rejection. The possibility that the endothelium in surviving allografts may eventually be replaced by cells of host genotype is important4 but

outside the scope of this report. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your

institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access

to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our

FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS ISCHEMIC WOUND REVASCULARIZATION BY THE STROMAL VASCULAR FRACTION RELIES ON HOST-DONOR HYBRID VESSELS Article Open

access 11 February 2023 CELLULAR AND MOLECULAR MECHANISMS OF SKIN WOUND HEALING Article 25 March 2024 A NEW FASCIOCUTANEOUS FLAP MODEL IDENTIFIES A CRITICAL ROLE FOR ENDOTHELIAL NOTCH

SIGNALING IN WOUND HEALING AND FLAP SURVIVAL Article Open access 02 August 2023 REFERENCES * Converse, J. M., Filler, M., and Ballantye, jun., D. L., _Transplantation_, 3, 22 (1965). Article

  CAS  Google Scholar  * Haller, J. A., Rauenhorst, J., Atkins, J., and Billingham, R. E., _Surg. Forum_ (American College of Surgeons), 17, 96 (1966). PubMed  Google Scholar  * Zarem, H.

A., _Surgery_, 66, 392 (1969). CAS  PubMed  Google Scholar  * Billingham, R. E., Brent, L., and Medawar, P. B., _Phil. Trans. Roy. Soc._, 239, 357 (1956). Article  ADS  Google Scholar  *

Lambert, P. B., _Transplantation_, 10, 463 (1970). Article  CAS  Google Scholar  * Zarem, H. A., Zweifach, B. W., and McGehee, J. M., _Amer. J. Phys._, 212, 1081 (1967). CAS  Google Scholar

  * Lambert, P. B., Frank, H. A., Bellman, S., and Friedman, E., _Angiology_, 14, 121 (1963). Article  CAS  Google Scholar  * Bellman, S., Velander, E., Frank, H. A., and Lambert, P. B.,

_Transplantation_, 2, 167 (1964). Article  CAS  Google Scholar  * Lambert, P. B., and Frank, H. A., _Science_, 155, 99 (1967). Article  ADS  CAS  Google Scholar  * Lambert, P. B., and Frank,

H. A., _J. Exp. Med._, 132, 868 (1970). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Surgery, Harvard Medical School and

Beth Israel Hospital, Boston, Massachusetts, 02125 PETER B. LAMBERT Authors * PETER B. LAMBERT View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND

PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE LAMBERT, P. Vascularization of Skin Grafts. _Nature_ 232, 279–280 (1971). https://doi.org/10.1038/232279a0 Download

citation * Received: 14 September 1970 * Revised: 22 November 1970 * Issue Date: 23 July 1971 * DOI: https://doi.org/10.1038/232279a0 SHARE THIS ARTICLE Anyone you share the following link

with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt

content-sharing initiative