Nature immunology - aging of the human immune system across the whole lifespan

AGING OF THE HUMAN IMMUNE SYSTEM ACROSS THE WHOLE LIFESPAN Wang et al. profile the evolution of peripheral immune cell diversity, function and interactions at the single-cell transcriptional

and protein levels, across eight distinct stages from birth to old age. The artwork conceptualizes the human peripheral immune system as a vibrant and evolving garden, where the flowers

symbolize the dynamic changes in various immune cell populations and states with the passage of life. See Wang et al. Image: Lulu Zhang, August Fireflies Technology; concept by: Ronghong Li

and Jun Pu, Renji Hospital, Shanghai Jiao Tong University School of Medicine. Cover design: Vanitha Selvarajan