Nature structural & molecular biology


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------------------------- FOCUS ON CHROMATIN In eukaryotes, the packaging of DNA by histones into chromatin has profound effects on transcription and other nuclear processes. Far from being


a uniform set of 'beads on a string', chromatin structure is remodeled and even modified, altering the accessibility of packaged genes to the factors involved in their regulation.


This special focus on chromatin features an Overview, six Reviews and a Perspective that describe how chromatin is built and subsequently altered at various structural levels, and the impact


of these events on fundamental biological processes involving DNA. Top of page REVIEWS FOCUS ON CHROMATIN HISTONE CHAPERONES: AN ESCORT NETWORK REGULATING HISTONE TRAFFIC - PP997 - 1007


Leanne De Koning, Armelle Corpet, James E Haber & Geneviève Almouzni doi:10.1038/nsmb1318 Abstract | Full Text | PDF (1,027 KB) ------------------------- FOCUS ON CHROMATIN COVALENT


MODIFICATIONS OF HISTONES DURING DEVELOPMENT AND DISEASE PATHOGENESIS - PP1008 - 1016 Sukesh R Bhaumik, Edwin Smith & Ali Shilatifard doi:10.1038/nsmb1337 Abstract | Full Text | PDF


(1,330 KB) ------------------------- FOCUS ON CHROMATIN CROSS-REGULATION OF HISTONE MODIFICATIONS - PP1017 - 1024 John A Latham & Sharon Y R Dent doi:10.1038/nsmb1307 Abstract | Full


Text | PDF (504 KB) ------------------------- FOCUS ON CHROMATIN HOW CHROMATIN-BINDING MODULES INTERPRET HISTONE MODIFICATIONS: LESSONS FROM PROFESSIONAL POCKET PICKERS - PP1025 - 1040 Sean


D Taverna, Haitao Li, Alexander J Ruthenburg, C David Allis & Dinshaw J Patel doi:10.1038/nsmb1338 Abstract | Full Text | PDF (2,290 KB) ------------------------- FOCUS ON CHROMATIN


TRANSCRIPTION AND RNAI IN HETEROCHROMATIC GENE SILENCING - PP1041 - 1048 Marc Bühler & Danesh Moazed doi:10.1038/nsmb1315 Abstract | Full Text | PDF (675 KB) -------------------------


FOCUS ON CHROMATIN GENE REGULATION THROUGH NUCLEAR ORGANIZATION - PP1049 - 1055 Tom Sexton, Heiko Schober, Peter Fraser & Susan M Gasser doi:10.1038/nsmb1324 Abstract | Full Text | PDF


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