Biomaterial design for proactive modulation of the complement system

Redesigning biomaterials to proactively modulate the complement system can reduce unintended immune responses and enhance their therapeutic efficacy. Access through your institution Buy or

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Google Scholar  Download references ACKNOWLEDGEMENTS This paper was supported by the National Natural Science Foundation of China (W2411085), Noncommunicable Chronic Diseases-National

Science and Technology Major Project (2023ZD0500700) and the Shanghai Municipal Health Commission (2022XD055). AUTHOR INFORMATION Author notes * These authors contributed equally: Adilijiang

Abudousu, Yunkai Tang. AUTHORS AND AFFILIATIONS * Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of

Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Adilijiang Abudousu, Yunkai Tang, Zhen Wang, Feng Lin 

& Wenguo Cui Authors * Adilijiang Abudousu View author publications You can also search for this author inPubMed Google Scholar * Yunkai Tang View author publications You can also search

for this author inPubMed Google Scholar * Zhen Wang View author publications You can also search for this author inPubMed Google Scholar * Feng Lin View author publications You can also

search for this author inPubMed Google Scholar * Wenguo Cui View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Wenguo

Cui. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Abudousu, A.,

Tang, Y., Wang, Z. _et al._ Biomaterial design for proactive modulation of the complement system. _Nat Rev Bioeng_ 3, 355–356 (2025). https://doi.org/10.1038/s44222-025-00281-x Download

citation * Published: 13 February 2025 * Issue Date: May 2025 * DOI: https://doi.org/10.1038/s44222-025-00281-x SHARE THIS ARTICLE Anyone you share the following link with will be able to

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