Tmem65 joins the mitochondrial ca2+ club

Garbincius et al. show that TMEM65, a mitochondrial transmembrane protein of unknown function, has a central role in efflux of calcium ions from the mitochondria. Mitochondrial calcium

efflux is crucial for maintaining mitochondrial calcium levels, which is important for metabolic homeostasis and mitochondrial health. Access through your institution Buy or subscribe This

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Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pharmacology, University of Washington, Seattle, WA, USA Yasemin Sancak Authors * Yasemin Sancak View

author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Yasemin Sancak. ETHICS DECLARATIONS COMPETING INTERESTS The author

declares no competing interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Sancak, Y. TMEM65 joins the mitochondrial Ca2+ club. _Nat Metab_ 7,

641–642 (2025). https://doi.org/10.1038/s42255-025-01271-4 Download citation * Published: 08 April 2025 * Issue Date: April 2025 * DOI: https://doi.org/10.1038/s42255-025-01271-4 SHARE THIS

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