Yap/taz phase separation for transcription

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YAP and TAZ, paralogous mammalian genes, act as the key transcriptional effectors of the Hippo pathway. Two recent reports show that both YAP and TAZ form liquid–liquid phase-separated


bodies that promote gene transcription by engaging in super-enhancers. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution


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(2002). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pharmacology and Moores Cancer Center, University of California, San


Diego, La Jolla, CA, USA J. Matthew Franklin & Kun-Liang Guan Authors * J. Matthew Franklin View author publications You can also search for this author inPubMed Google Scholar *


Kun-Liang Guan View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Kun-Liang Guan. ETHICS DECLARATIONS COMPETING


INTERESTS K.L.G. is a cofounder of and has equity interest in Vivace Therapeutics. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Franklin, J.M., Guan,


KL. YAP/TAZ phase separation for transcription. _Nat Cell Biol_ 22, 357–358 (2020). https://doi.org/10.1038/s41556-020-0498-8 Download citation * Published: 23 March 2020 * Issue Date: April


2020 * DOI: https://doi.org/10.1038/s41556-020-0498-8 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable


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