Critical appraisal of papers reporting recommendation on sarcopenia using the agree ii tool: a euroaim initiative

ABSTRACT BACKGROUND/OBJECTIVES The growing interest of medical community about sarcopenia resulted in the production of several clinical practice guidelines (CPGs), with an unavoidable

variability in terms of the overall quality of those publications. Our aim is to evaluate the quality of CPGs on sarcopenia using the AGREE II instrument. SUBJECTS/METHODS We performed an

online literature search for sarcopenia CPGs using different databases. Four independent reviewers evaluated the quality of CPGs using the AGREE II instrument. To classify the quality of

each guideline, we defined specific thresholds of final score: high-quality if five or more domains scored >60%; average-quality if three or four domains scored >60%; low-quality if ≤2

domains scored >60%. RESULTS Our literature search yielded 315 articles, and after applying exclusion criteria our final analysis included 19 CPGs. The overall quality of CPGs was

remarkable, as 13/19 (68.4%) were considered of “high-quality” CPGs, with more than four domains reached a score higher than 60%. “Scope and Purpose” and “Clarity of Presentations” had the

best domain results (78.4% and 73.8%, respectively), while the two domains with the lowest scores were “Rigor of Development” and “Applicability” (61.5% and 58.7%, respectively).

Interobserver variability ranged between moderate (0.624) and fair (0.275). CONCLUSIONS Our study showed that the overall quality of CPGs about sarcopenia was noteworthy, as more than

two-third of paper obtained a “high-quality” score. The domain “applicability” had the lowest score, suggesting that emphasis should be put on possible strategies for helping other doctors

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Article 11 November 2021 THE EFFECTIVENESS OF OPTIMAL EXERCISE-BASED STRATEGY FOR PATIENTS WITH HIP FRACTURE: A SYSTEMATIC REVIEW AND BAYESIAN NETWORK META-ANALYSIS Article Open access 29

June 2023 SARCOPENIA IN HOSPITALIZED GERIATRIC PATIENTS: INSIGHTS INTO PREVALENCE AND ASSOCIATED PARAMETERS USING NEW EWGSOP2 GUIDELINES Article Open access 15 October 2020 REFERENCES *

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  Download references ACKNOWLEDGEMENTS This work has been conducted within the framework of the EuroAIM, research platform of the European Institute for Biomedical Research

(http://www.eibir.org/scientific-activities/joint-initiatives/euroaim/). This study was supported by the Italian Ministry of Health (Ricerca Corrente). AUTHOR INFORMATION AUTHORS AND

AFFILIATIONS * IRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy Carmelo Messina, Jacopo Antonino Vitale, Luigi Pedone, Vito Chianca, Domenico Albano & 

Luca Maria Sconfienza * Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Via Carlo Pascal, 36, 20133, Milan, Italy Carmelo Messina, Salvatore Gitto & 

Luca Maria Sconfienza * Scuola di Specializzazione in Radiodiagnostica, Università degli Studi di Milano, Via Festa del Perdono 7, 20122, Milan, Italy Ilaria Vicentin * Sezione di Scienze

Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Università degli Studi di Palermo, Via del Vespro 127, 90127, Palermo, Italy Domenico Albano Authors * Carmelo

Messina View author publications You can also search for this author inPubMed Google Scholar * Jacopo Antonino Vitale View author publications You can also search for this author inPubMed 

Google Scholar * Luigi Pedone View author publications You can also search for this author inPubMed Google Scholar * Vito Chianca View author publications You can also search for this author

inPubMed Google Scholar * Ilaria Vicentin View author publications You can also search for this author inPubMed Google Scholar * Domenico Albano View author publications You can also search

for this author inPubMed Google Scholar * Salvatore Gitto View author publications You can also search for this author inPubMed Google Scholar * Luca Maria Sconfienza View author

publications You can also search for this author inPubMed Google Scholar CONTRIBUTIONS All authors contributed to meet the ICMJE Recommendations for authorship, having provided: 1.

Substantial contributions to the conception and design (CM, DA), acquisition (IV), or analysis and interpretation of data (LP, SG, JV, VC). 2. Drafting the paper (CM, DA) or revising it

critically for important intellectual content (CM, LMS). 3. Final approval of the version to be published (all authors). 4. All authors agreed to be accountable for all aspects of the work

in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. CORRESPONDING AUTHOR Correspondence to Carmelo Messina.

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CITE THIS ARTICLE Messina, C., Vitale, J.A., Pedone, L. _et al._ Critical appraisal of papers reporting recommendation on sarcopenia using the AGREE II tool: a EuroAIM initiative. _Eur J

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