Personal care product use as a predictor of urinary concentrations of certain phthalates, parabens, and phenols in the hermosa study

ABSTRACT Use of personal care products, such as makeup, soaps, and sunscreen, may expose adolescent girls to potential endocrine disruptors, including phthalates, parabens, and other

phenols. We evaluated the relationship between recent self-reported personal care product use and concentrations for urinary metabolites of phthalates, parabens, triclosan, and

benzophenone-3 (BP-3) in 100 Latina adolescents. Girls who reported using makeup every day vs. rarely/never had higher urinary concentrations of monoethyl phthalate (MEP) (102.2 ng/mL vs.

52.4 ng/mL, _P_-value: 0.04), methyl paraben (MP) (120.5 ng/mL vs. 13.4 ng/mL, _P_-value < 0.01), and propyl paraben (PP) (60.4 ng/mL vs. 2.9 ng/mL, _P_-value < 0.01). Girls who

reported recent use of specific makeup products, including foundation, blush, and mascara, had higher urinary concentrations of MEP, mono-n-butyl phthalate (MBP), MP, and PP. Use of Colgate

Total toothpaste was associated with 86.7% higher urinary triclosan concentrations. Use of sunscreen was associated with 57.8% higher urinary concentrations of BP-3. Our findings suggest

that personal care product use is associated with higher exposure to certain phthalates, parabens, and other phenols in urine. This may be especially relevant in adolescent girls who have

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This paper was supported by California Breast Cancer Research Program grant 18BB-1800 and NIEHS grant 1R21ES024909. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Center for Environmental

Research and Children’s Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA Kimberly P. Berger, Katherine R. Kogut, Asa Bradman & Kim G. Harley *

Environmental Health Laboratory, California Department of Public Health, Richmond, CA, USA Jianwen She, Qi Gavin & Rana Zahedi * Clinica de Salud del Valle de Salinas, Salinas, CA, USA

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permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Berger, K.P., Kogut, K.R., Bradman, A. _et al._ Personal care product use as a predictor of urinary concentrations of certain phthalates,

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Nature SharedIt content-sharing initiative KEYWORDS * Personal care products * Product use * Phthalates * Parabens * Triclosan * Benzophenone-3