Nasal continuous positive airway pressure (ncpap) facilitates extubation of infants 600 to 125og without unwanted side-effects: results of a randomised controlled trial


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BACKGROUND: Previous studies reached conflicting conclusions regarding the benefits of NCPAP for premature infants no longer requiring an endotracheal tube and did not address other neonatal


outcomes .OBJECTIVES - Primary: to determine if extubation to NCPAP results in a greater proportion of infants remaining free of additional support for one week compared with those


extubated directly to headbox oxygen (HB). Secondary: to compare rates of feed intolerance, chronic lung disease, spesis, retinopathy of prematurity and intraventricular haemorrhage


.MANOEUVRE: Infants randomly allocated to either NCPAP (3.0 Portex tube inserted 2.5 cm) or HB. RESULTS: 47 infants extubated to NCPAP, mean (SD) BWt 960 (182) g and 45 to HB 927 (157) g.


Successful extubation in 66% of the NCPAP group vs 40% of headbox (p = 0.013). No significant differences in secondary outcomes. CONCLUSIONS: NCPAP applied following endotracheal extubation


results in a statistically significant and clinically important improvement in success rate without an increased incidence of unwanted side-effects. AUTHOR INFORMATION AUTHORS AND


AFFILIATIONS * Royal Women's Hospital, Melbourne, Australia Peter G Davis, Robert R Jankov, Lex W Doyle & Philip N Henschke Authors * Peter G Davis View author publications You can


also search for this author inPubMed Google Scholar * Robert R Jankov View author publications You can also search for this author inPubMed Google Scholar * Lex W Doyle View author


publications You can also search for this author inPubMed Google Scholar * Philip N Henschke View author publications You can also search for this author inPubMed Google Scholar ADDITIONAL


INFORMATION Philip N. Henschke (Spon by Barbara K. Schmidt) RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Davis, P., Jankov, R., Doyle, L. _et al._


Nasal Continuous Positive Airway Pressure (Ncpap) Facilitates Extubation of Infants 600 To 125Og Without Unwanted Side-Effects: Results of A Randomised Controlled Trial. _Pediatr Res_ 42,


403 (1997). https://doi.org/10.1203/00006450-199709000-00127 Download citation * Issue Date: 01 September 1997 * DOI: https://doi.org/10.1203/00006450-199709000-00127 SHARE THIS ARTICLE


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