Lung function in newborn infants with tachypnea of unknown cause


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ABSTRACT ABSTRACT. Twenty-one infants with tachypnea (f > 60/min) lasting more than 2 h and diagnosed as mild respiratory disease or pulmonary maladaptation according to previously


presented criteria were studied during the course of the disease and after clinical recovery. Lung physiology (total and alveolar ventilation, efficiency and distribution of ventilation,


functional residual capacity, and lung mechanics) was studied in combination with clinical data. The pathophysiological findings were characterized by increased total ventilation but normal


alveolar ventilation, reduced efficiency of ventilation but more even distribution of ventilation (nitrogen elimination pattern) during disease than after clinical recovery, hyperinflation,


reduced dynamic lung compliance but unaffected specific lung conductance. Infants with low gestational ages were most severely affected and had longer duration of disease than full-term


infants. Our findings suggest that this condition is caused by small airway disease. Disturbances in normal pulmonary adaptation with abnormal retention of lung fluid is the most probable


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USING THE INSUFFLATOR/EXSUFFLATOR TECHNIQUE: AN OBSERVATIONAL STUDY Article Open access 29 April 2022 ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pediatrics I,


Gothenburg University and Research Laboratory of Medical Electronics, Chalmers University of Technology, Göteborg, Sweden Kenneth Sandberg, Bengt-Arne Sjöqvist, Ola Hjalmarson & Torsten


Olsson Authors * Kenneth Sandberg View author publications You can also search for this author inPubMed Google Scholar * Bengt-Arne Sjöqvist View author publications You can also search for


this author inPubMed Google Scholar * Ola Hjalmarson View author publications You can also search for this author inPubMed Google Scholar * Torsten Olsson View author publications You can


also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Sandberg, K., Sjöqvist, BA., Hjalmarson, O. _et al._


Lung Function in Newborn Infants with Tachypnea of Unknown Cause. _Pediatr Res_ 22, 581–586 (1987). https://doi.org/10.1203/00006450-198711000-00020 Download citation * Received: 16 January


1987 * Accepted: 30 June 1987 * Issue Date: 01 November 1987 * DOI: https://doi.org/10.1203/00006450-198711000-00020 SHARE THIS ARTICLE Anyone you share the following link with will be able


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