1635 effects of intensive in-hospital therapy on lung functions and exercise tolerance in cystic fibrosis (cf)


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ABSTRACT There is little information on the objective benefits of inhospital therapy in CF. We, therefore, studied the effects of a 13 day ± 2.6 SD (range 10-18 days) admission on lung


functions and exercise capacity in 15 CF patients with moderate to severe disease. Treatment consisted of intravenous antibiotics, postural drainage and exercise therapy. We measured resting


vital capacity (VC), residual volume (RV), total lung capacity (TLC), forced expired volume in 1 second (FEV1), specific airway conductance (SG), arterial oxygen saturation (SaO2), and


exercise adaptation and tolerance shortly after admission and before discharge. Adaptation to exercise was evaluated by the work capacity (Watts/kg), peak heart rate (PHR), exercise-induced


changes in SaO2 and the ratio of PHR to peak W/kg. The results show that our 2-week treatment program brought about significant, objective improvements in lung function, exercise tolerance


and exercise adaptation in CF patients. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * State Univ. of N.Y., Children's Hospital, Dept. of Pediatrics, Buffalo, N.Y. Frank J


Cerny & Gerd J Cropp Authors * Frank J Cerny View author publications You can also search for this author inPubMed Google Scholar * Gerd J Cropp View author publications You can also


search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Cerny, F., Cropp, G. 1635 EFFECTS OF INTENSIVE IN-HOSPITAL


THERAPY ON LUNG FUNCTIONS AND EXERCISE TOLERANCE IN CYSTIC FIBROSIS (CF). _Pediatr Res_ 15 (Suppl 4), 715 (1981). https://doi.org/10.1203/00006450-198104001-01652 Download citation * Issue


Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01652 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link


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