1121 echocardiographic evidence for impaired myocardial performance in children with type i diabetes mellitus


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ABSTRACT Myocardial performance was assessed by M-mode echocardiography in 33 children (6 8/12-19 3/12 yr) with Type I diabetes mellitus and in 51 normal children (6 2/12-18 8/12). Left


ventricular end systolic dimension (LVESD), and left ventricular end systolic volume/M2 (LVESV/M2) were greater in diabetics than controls. Left ventricular ejection fraction (LVEF), minor


axis shortening (MAS), and velocity of circumferential fiber shortening (VCF) were less in diabetics than controls. Hgb A1 levels in children with diabetes (15.5±0.6%, range 10.1-22.2%,


normal 5.9-8.7%) correlated with clinical assessment of control (p<.01). Age, Hgb A1, duration of diabetes, and clinical assessment did not predict myocardial function. We conclude that


there is impaired myocardial contractility in some children with insulin-dependent diabetes not correlated with duration of diabetes, age, clinical assessment of control, or Hgb A1. The


long-term significance of this finding and the effect of improved control remain to be assessed. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Pritzker School of Medicine, Univ.


of Chicago, Michael Reese Hospital, Dept. of Pediatrics, Chicago Nancy E Friedman, Lynne L Levitsky, Deborah V Edidin, Dolores A Vitullo, Samuel J Lacina & Pipit Chiemmongkoltip Authors


* Nancy E Friedman View author publications You can also search for this author inPubMed Google Scholar * Lynne L Levitsky View author publications You can also search for this author


inPubMed Google Scholar * Deborah V Edidin View author publications You can also search for this author inPubMed Google Scholar * Dolores A Vitullo View author publications You can also


search for this author inPubMed Google Scholar * Samuel J Lacina View author publications You can also search for this author inPubMed Google Scholar * Pipit Chiemmongkoltip View author


publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Friedman, N., Levitsky, L.,


Edidin, D. _et al._ 1121 ECHOCARDIOGRAPHIC EVIDENCE FOR IMPAIRED MYOCARDIAL PERFORMANCE IN CHILDREN WITH TYPE I DIABETES MELLITUS. _Pediatr Res_ 15 (Suppl 4), 629 (1981).


https://doi.org/10.1203/00006450-198104001-01147 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01147 SHARE THIS ARTICLE Anyone you share the


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