Biomarkers from liquid biopsy | Nature Reviews Urology


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Access through your institution Buy or subscribe Researchers have identified liquid-biopsy signatures indicative of extracapsular prostate cancer, demonstrating that computationally guided


proteomics can be used to discover biomarkers from samples obtained in a noninvasive manner. Kim and colleagues combined quantitative targeted proteomics with computational biology to


discover robust proteomic signatures for prostate cancer. Initially, 133 proteins were identified in expressed prostatic secretions in urine from men with prostate cancer. These proteins


were validated in samples from 74 men, which resulted in 34 proteins demonstrating potential for classifying patients based on disease status. This is a preview of subscription content,


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OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Kim, Y. _ et al_. Targeted proteomics identifies liquid-biopsy signatures


for extracapsular prostate cancer. _Nat. Commun._ http://dx.doi.org/10.1038/ncomms11906 (2016) Download references Authors * Louise Stone View author publications You can also search for


this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Stone, L. Biomarkers from liquid biopsy. _Nat Rev Urol_ 13, 434


(2016). https://doi.org/10.1038/nrurol.2016.133 Download citation * Published: 19 July 2016 * Issue Date: August 2016 * DOI: https://doi.org/10.1038/nrurol.2016.133 SHARE THIS ARTICLE Anyone


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