Holep—a steep learning curve but better for patients

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Access through your institution Buy or subscribe A new prospective trial has shown that holmium laser enucleation of the prostate (HoLEP) is associated with a lower risk of haemorrhage and


shorter postprocedure bladder irrigation time than bipolar transurethral resection of the prostate (TURP), the current gold standard. Despite these similarities, the perioperative data were


different between the two groups, which might have some important implications for patients and surgeons. For example, patients in the HoLEP group required shorter periods of bladder


irrigation to resolve haematuria than the men who underwent TURP. Also, the amount of material removed from the prostate was considerably higher in men who had HoLEP, which was reflected in


a sharper drop in PSA levels after surgery. “HoLEP broadens the scope of minimally invasive treatments for men with BPH,” lead investigator Zhong Wang explains. “HoLEP can be combined with


mechanical morcellation, we can expose the surgical capsule easily and, importantly, treat even very large prostates.” TURP, by contrast, is associated with a higher risk of bleeding when


treating very enlarged prostates. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12


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REFERENCES ORIGINAL RESEARCH PAPER * Chen, Y.-B. _ et al_. A prospective, randomized clinical trial comparing plasmakinetic resection of the prostate with holmium laser enucleation of the


prostate based on a 2-year followup. _J. Urol._ 189, 217–222 (2013) Article  PubMed  Google Scholar  FURTHER READING * van Rij, S. & Gilling, P. J. In 2013, holmium laser enucleation of


the prostate (HoLEP) may be the new 'gold standard'. _Curr. Urol. Rep._ 13, 427–432 (2012) Article  PubMed  Google Scholar  Download references Authors * Mina Razzak View author


publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Razzak, M. HoLEP—a steep


learning curve but better for patients. _Nat Rev Urol_ 10, 66 (2013). https://doi.org/10.1038/nrurol.2012.236 Download citation * Published: 11 December 2012 * Issue Date: February 2013 *


DOI: https://doi.org/10.1038/nrurol.2012.236 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not


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