The choice of antipsychotics in schizophrenia


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In light of claims of improved efficacy and lower incidence of adverse effects compared with older drugs, second-generation antipsychotics have emerged as the predominant treatment for


schizophrenia. A new meta-analysis concludes that the difference in efficacy between newer and older agents is small, and the current classification scheme for antipsychotics does not


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  CAS  Google Scholar  Download references AUTHOR INFORMATION Author notes * R. L. MargolisJohns Hopkins Schizophrenia Program, Department of Psychiatry, Johns Hopkins University School of


Medicine, CMSC 8–121, 600 N. Wolfe Street, Baltimore, MD 21287, USA rmargoli@jhmi.edu AUTHORS AND AFFILIATIONS * Department of Psychiatry, Johns Hopkins University School of Medicine,


Baltimore, MD, USA Russell L. Margolis Authors * Russell L. Margolis View author publications You can also search for this author inPubMed Google Scholar ETHICS DECLARATIONS COMPETING


INTERESTS R. L. Margolis is a consultant for AstraZeneca. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Margolis, R. The choice of antipsychotics in


schizophrenia. _Nat Rev Neurol_ 5, 308–310 (2009). https://doi.org/10.1038/nrneurol.2009.68 Download citation * Issue Date: June 2009 * DOI: https://doi.org/10.1038/nrneurol.2009.68 SHARE


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