Evolving expression patterns | Nature Reviews Neuroscience


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Access through your institution Buy or subscribe Differences in gene expression patterns are thought to be drivers of evolutionary changes in brain organization and function. Sousa _et al_.


compared the transcriptomes of 16 brain regions in humans, chimpanzees and macaque monkeys, revealing brain-wide, regional and cell type-specific differences in gene expression between


species, and identifying a population of tyrosine hydroxylase-expressing interneurons that are enriched in the human striatum and neocortex. These patterns of gene expression may underlie


some of the behavioural and cognitive differences between species, as well as the human-specific vulnerability to some diseases. This is a preview of subscription content, access via your


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Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional


subscriptions * Read our FAQs * Contact customer support REFERENCES * Sousa, A. M. M. et al. Molecular and cellular reorganization of neural circuits in the human lineage. _Science_ 358,


1027–1032 (2017) Article  CAS  Google Scholar  Download references Authors * Katherine Whalley View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND


PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Whalley, K. Evolving expression patterns. _Nat Rev Neurosci_ 19, 7 (2018). https://doi.org/10.1038/nrn.2017.158


Download citation * Published: 14 December 2017 * Issue Date: January 2018 * DOI: https://doi.org/10.1038/nrn.2017.158 SHARE THIS ARTICLE Anyone you share the following link with will be


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