Correction: occurrence of leukaemia following gene therapy of x-linked scid


Play all audios:

_Nature Rev. Cancer_ 3, 477–488 (2003) On page 482 of this article, a recent report by S. Hacein-Bey-Abina _et al_. was inadvertently omitted from the list of citations in the legend of


Figure 2a. The text and reference should have been: See also Refs 14, 18 and 99. THE FIRST REPORT OF A MONOCLONAL T CELL LYMPHOPROLIFERATIVE SYNDROME, DETECTED 30 MONTHS AFTER GENE THERAPY.


WITHIN FOUR MONTHS, THE PATIENT DEVELOPED A MAJOR HYPERLYMPHOCYTOSIS AND HEPATOSPLENOMEGALY. A SINGLE VECTOR INTEGRATION WAS FOUND WITHIN THE _LMO2_ LOCUS, ASSOCIATED WITH ABERRANT LMO2


EXPRESSION. The authors also want to point out that Dr Fischer and his colleagues describe the clonal expansions that were observed in their two patients as 'leukaemia-like


lymphoproliferative disease'. The general term of 'leukaemia', without further qualification, was used in this review. REFERENCES * Hacein-Bey-Abina, S. et al. A serious


adverse event after successful gene therapy for X-linked severe combined immunodeficiency. _N. Engl. J. Med._ 348, 255–256 (2003). Article  Google Scholar  Download references Authors *


Donald B. Kohn View author publications You can also search for this author inPubMed Google Scholar * Michel Sadelain View author publications You can also search for this author inPubMed 


Google Scholar * Joseph C. Glorioso View author publications You can also search for this author inPubMed Google Scholar ADDITIONAL INFORMATION The online version of the original article can


be found at 10.1038/nrc1122 RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kohn, D., Sadelain, M. & Glorioso, J. Correction: Occurrence of


leukaemia following gene therapy of X-linked SCID. _Nat Rev Cancer_ 3, 883 (2003). https://doi.org/10.1038/nrc1236 Download citation * Issue Date: November 2003 * DOI:


https://doi.org/10.1038/nrc1236 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently


available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative