Evaluation of a new rapid bacteriophage-based method for the drug susceptibility testing of mycobacterium tuberculosis

Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this

journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now

Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer

support REFERENCES * Kochi, A. The global tuberculosis situation and the new control strategy of the World Health Organization. _Tubercle_ 72, 1–6 (1991). Article  CAS  Google Scholar  *

Snider, D.E., Raviglione, M. & Kochi, A. Global burden of tuberculosis. in _Tuberculosis: Pathogenesis, Protection and Control_. (ed. Bloom,B. R.) 3–11 (American Society for

Microbiology, Washington, DC, 1994). Chapter  Google Scholar  * Selwyn, P.A., Hartel, D. & Lewis, I.A. A prospective study of the risk of tuberculosis among intravenous drug abusers with

human immunodeficiency virus infection. _N. Engl. J. Med._ 320, 545–550 (1989). Article  CAS  Google Scholar  * Valway, S.E. _et al_. Multidrug resistant tuberculosis in the New York State

Prison System 1990–1991. _J. Infect. Dis._ 170, 151–156 (1994). Article  CAS  Google Scholar  * Groothuis, D.G. & Yates, M.D. _Diagnostic and Public Health Mycobacteriology_. (Bureau of

Hygiene and Tropical Diseases, London, 1991). Google Scholar  * Hawkey, P.M. The role of polymerase chain reaction in the diagnosis of mycobacterial infections. _Rev. Med. Microbiol._ 5,

21–32 (1994). Article  Google Scholar  * Miller, N., Hernandez, S.G. & Cleary, T.J. Evaluation of Gen-Probe amplified _Mycobacterium tuberculosis_ Direct Test and PCR for direct

detection of _Mycobacterium tuberculosis_ in clinical specimens. _J. Clin. Microbiol._ 32, 393–397 (1994). CAS  PubMed  PubMed Central  Google Scholar  * Drobniewski, F.A. & Pozniak,

A.L. Molecular diagnosis, detection of drug resistance and epidemiology of tuberculosis. _Br. J. Hosp. Med._ 56, 205–208 (1996). Google Scholar  * De Beenhouwer, H. _et al_. Rapid detection

of rifampicin resistance in sputum and biopsy specimens from tuberculosis patients by PCR and line probe assay. _Tuber. Lung. Dis._ 76, 425–430 (1995). Article  CAS  Google Scholar  *

Telenti, A. _et al_. Detection of rifampicin-resistance mutations in _Mycobacterium tuberculosis_. _Lancet_ 341, 647–650 (1993). Article  CAS  Google Scholar  * Vareldzis, B.P. _et al_.

Drug-resistant tuberculosis: Laboratory issues. _Tuber. Lung Dis._ 75, 1–7 (1994). Article  CAS  Google Scholar  * Youatt, J. A review of the action of isoniazid. _Am. Rev. Respir. Dis._ 99,

729–749 (1969). CAS  PubMed  Google Scholar  * David, H.L., Clavel-Sores, S. & Clement, F. Adsorption and growth of the bacteriophage D29 in selected mycobacteria. _Ann. Inst. Pasteur

Virol._ 131E, 167–184 (1980). Article  Google Scholar  * Jacobs, W.R., Jr. _et al_. Rapid assessment of drug susceptibilities by means of luciferase reporter phage. _Science_ 260, 819–822

(1993). Article  CAS  Google Scholar  * Foley-Thomas, E.M., Whipple, D.L., Bermudez, L.E. & Barletta, R.G. Phage infection, transfection and transformation of _Mycobacterium avium and

Mycobacterium paratuberculosis_. _Microbiology_ 141, 1173–1181 (1995). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Public Health

Laboratory Service Mycobacterium Reference Unit (MRU), Dulwich Hospital, EastDulwich Grove, Dulwich, London, SE22 8QF, UK Stuart Mark Wilson, Zubaida Al-Suwaidi & Francis Drobniewski *

Department of Clinical Sciences, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK Zubaida Al-Suwaidi, Ruth McNerney & John Porter Authors * Stuart

Mark Wilson View author publications You can also search for this author inPubMed Google Scholar * Zubaida Al-Suwaidi View author publications You can also search for this author inPubMed 

Google Scholar * Ruth McNerney View author publications You can also search for this author inPubMed Google Scholar * John Porter View author publications You can also search for this author

inPubMed Google Scholar * Francis Drobniewski View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS

ARTICLE CITE THIS ARTICLE Wilson, S., Al-Suwaidi, Z., McNerney, R. _et al._ Evaluation of a new rapid bacteriophage-based method for the drug susceptibility testing of _Mycobacterium

tuberculosis_. _Nat Med_ 3, 465–468 (1997). https://doi.org/10.1038/nm0497-465 Download citation * Issue Date: 01 April 1997 * DOI: https://doi.org/10.1038/nm0497-465 SHARE THIS ARTICLE

Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided

by the Springer Nature SharedIt content-sharing initiative