Cardiotoxicity in a dish: new insights for personalized therapy

A recent study identifies differences in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes from patients with breast cancer who were treated with doxorubicin and either did

or did not develop cardiotoxicity. The results open up new avenues for the development of personalized therapy and the prevention of cardiotoxicity. Access through your institution Buy or

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S.M. _Nat. Rev. Cardiol._ 12, 547–558 (2015). Article  CAS  Google Scholar  * Burridge, P.W. et al. _Nat. Med._ 22, 547–556 (2016). Article  CAS  Google Scholar  * Burridge, P.W. et al.

_Nat. Methods_ 11, 855–860 (2014). Article  CAS  Google Scholar  * Slamon, D.J. et al. _N. Engl. J. Med._ 344, 783–792 (2001). Article  CAS  Google Scholar  Download references AUTHOR

INFORMATION AUTHORS AND AFFILIATIONS * Mitch Biermann and Timothy J. Kamp are in the Departments of Medicine and Cell and Regenerative Biology, School of Medicine and Public Health,

University of Wisconsin–Madison, Madison, Wisconsin, USA, and the Stem Cell and Regenerative Medicine Center, University of Wisconsin–Madison, Madison, Wisconsin, USA., Mitch Biermann & 

Timothy J Kamp Authors * Mitch Biermann View author publications You can also search for this author inPubMed Google Scholar * Timothy J Kamp View author publications You can also search for

this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Timothy J Kamp. ETHICS DECLARATIONS COMPETING INTERESTS T.J.K. is a consultant for Cellular Dynamics

International. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Biermann, M., Kamp, T. Cardiotoxicity in a dish: new insights for personalized therapy.

_Nat Med_ 22, 459–460 (2016). https://doi.org/10.1038/nm.4095 Download citation * Published: 05 May 2016 * Issue Date: May 2016 * DOI: https://doi.org/10.1038/nm.4095 SHARE THIS ARTICLE

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