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Ossendorf C et al. (2007) Treatment of posttraumatic and focal osteoarthritic cartilage defects of the knee with autologous polymer-based three-dimensional chondrocyte grafts: two year
clinical results. Arthritis Res Ther 9: R41
Autologous chondrocyte implantation to treat knee chondral lesions is technically difficult and can lead to complications. Second-generation implants, which use the patient's autologous
chondrocytes embedded in a bioreabsorbable gel polymer scaffold, are easier for surgeons to handle. Ossendorf et al. evaluated the efficacy of one such implant, BioSeed®-C (BioTissue
Technologies GmbH, Germany), at regenerating articular cartilage.
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