Could calorie restriction truly make you live longer?

Access through your institution Buy or subscribe Heilbronn LK _ et al_. (2006) Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in

overweight individuals: a randomized controlled trial. _JAMA_ 295: 1539–1548 Researchers are now a step closer to answering that question, following publication of a study that investigated

the effects of a 6-month calorie-restricted diet on several biomarkers of metabolic adaptation and oxidative stress. Heilbronn _ et al_. found that prolonged calorie restriction reduced

fasting insulin levels and body temperature (both factors are associated with longevity in animal studies). Their findings support the theory that caloric restriction is associated with a

greater decrease in energy expenditure than would be expected to result solely from a reduction in metabolic mass. This is a preview of subscription content, access via your institution

ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article *

Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn

about institutional subscriptions * Read our FAQs * Contact customer support RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Could calorie restriction

truly make you live longer?. _Nat Rev Endocrinol_ 2, 362 (2006). https://doi.org/10.1038/ncpendmet0208 Download citation * Issue Date: July 2006 * DOI: https://doi.org/10.1038/ncpendmet0208

SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to

clipboard Provided by the Springer Nature SharedIt content-sharing initiative