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To identify the association between birth weight (BW)-for-gestational age (GA) and pulmonary hypertension (PHTN) at 36 weeks in infants with moderate–severe bronchopulmonary dysplasia (BPD).
In this retrospective cohort study, we followed 138 premature infants (⩽28 weeks) with moderate and severe BPD (National Institutes of Health consensus definition) born at Prentice Women’s
Hospital between 2005 and 2009. BW percentiles were calculated using the Fenton growth curve for premature infants. PHTN was determined using a standardized algorithm of echocardiogram
review at 36 weeks. Logistic regression was used to evaluate the associations between BW percentile subgroups and PHTN, taking into account antenatal and neonatal factors that were related
to PHTN.
PHTN was associated with small BW-for-GA, ranging from thresholds of