A case of extensive aplasia cutis congenita with underlying skull defect and central nervous system malformation: discussion of large skin defects, complications, treatment and outcome

ABSTRACT Aplasia Cutis Congenita (ACC) is a rare condition characterized by the absence of a portion of skin at birth. Skin defects are usually small (0.5 to 3 cm) and located on the scalp.

Although there can be other physical or genetic abnormalities, ACC is most often a benign isolated condition. Rarely is an underlying bony defect present, and this association increases the

rate of complications. We report a case of a newborn male with ACC of the entire crown and vertex scalp, non-ossified parietal skull and dysplastic corpus callosum. The patient's skull

and skin defects were treated non-surgically, and he recovered well. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution

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about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS ADDITIONAL FINDINGS OF TIBIAL DYSPLASIA IN A MALE WITH OROFACIODIGITAL

SYNDROME TYPE XVI Article Open access 31 March 2022 TYPE 2 CONGENITAL GENERALIZED LIPODYSTROPHY WITH A HETEROZYGOUS MISSENSE NOTCH2 MUTATION Article 18 January 2022 _BCL11B_-RELATED DISEASE:

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AUTHORS AND AFFILIATIONS * University of North Carolina School of Medicine, Chapel Hill, NC, USA A Burkhead * Department of Dermatology, University of North Carolina, Chapel Hill, NC, USA G

Poindexter & D S Morrell Authors * A Burkhead View author publications You can also search for this author inPubMed Google Scholar * G Poindexter View author publications You can also

search for this author inPubMed Google Scholar * D S Morrell View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to A

Burkhead. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Burkhead, A., Poindexter, G. & Morrell, D. A case of extensive Aplasia Cutis Congenita with

underlying skull defect and central nervous system malformation: discussion of large skin defects, complications, treatment and outcome. _J Perinatol_ 29, 582–584 (2009).

https://doi.org/10.1038/jp.2008.250 Download citation * Received: 05 July 2008 * Revised: 21 November 2008 * Accepted: 08 December 2008 * Published: 29 July 2009 * Issue Date: August 2009 *

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currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * aplasia cutis congenita * bony defect * sagittal sinus

hemorrhage