- Select a language for the TTS:
- UK English Female
- UK English Male
- US English Female
- US English Male
- Australian Female
- Australian Male
- Language selected: (auto detect) - EN
Play all audios:
Human microsomal and soluble epoxide hydrolases (mEH and sEH) are enzymes that metabolize xenobiotic molecules. We screened DNA from 48 Japanese individuals for single-nucleotide
polymorphisms (SNPs) in both genes by direct sequencing of the entire genomic regions containing EPHX1 and EPHX2, except for repetitive elements. This approach identified 33 SNPs in the
EPHX1 gene; 6 of them were located in the 5′ flanking region, 17 in introns, 8 in exons, and 2 in the 3′ flanking region. In the EPHX2 gene, we identified 36 SNPs, including 4 in the 5′
flanking region, 24 in introns, 5 in exons, and 3 in the 3′ flanking region, as well as one insertion/deletion polymorphism in the 5′ flanking region. These variants may contribute to a more
precise understanding of the nature of correlations between genotypes and disease-susceptibility phenotypes that have been postulated in regard to human microsomal and soluble epoxide
hydrolases.
Anyone you share the following link with will be able to read this content:
