The distribution of the group-specific component (gc) subtypes in japanese

SUMMARY The distribution of Gc subtypes in a sample from 310 unrelated healthy Japanese living in Tokyo was examined by a slab polyacrylamide gel isoelectrofocusing followed by

immunofixation. At least 9 phenotypes were distinguished which can be ascribed to four alleles:_Gc_ 1F,_Gc_ 1S,_Gc_ 2 and_Gc_ J. The allele frequencies were 0.4656, 0.2590, 0.2574 and

0.0180, respectively. It was confirmed that_Gc_ J has a polymorphic frequency in Japanese. Furthermore, two unusual phenotypes were encountered, one with a variant Gc 1 and the other with a

variant Gc 2 protein, indicating the occurrence in Japanese of two further Gc alleles. SIMILAR CONTENT BEING VIEWED BY OTHERS POPULATION-SPECIFIC DIVERSITY OF THE IMMUNOGLOBULIN CONSTANT

HEAVY G CHAIN (IGHG) GENES Article Open access 04 December 2021 IDENTIFICATION-DETECTION GROUP TESTING PROTOCOLS FOR COVID-19 AT HIGH PREVALENCE Article Open access 28 February 2022

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INFORMATION AUTHORS AND AFFILIATIONS * Department of Anthropology, Faculty of Science, The University of Tokyo, Tokyo, Japan Keiichi Omoto * First Department of Internal Medicine, Faculty of

Medicine, The University of Tokyo, Tokyo, Japan Kazuhiko Miyake Authors * Keiichi Omoto View author publications You can also search for this author inPubMed Google Scholar * Kazuhiko

Miyake View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Omoto, K.,

Miyake, K. The distribution of the group-specific component (Gc) subtypes in Japanese. _Jap J Human Genet_ 23, 119–125 (1978). https://doi.org/10.1007/BF02001792 Download citation *

Received: 13 February 1978 * Published: 01 June 1978 * Issue Date: June 1978 * DOI: https://doi.org/10.1007/BF02001792 SHARE THIS ARTICLE Anyone you share the following link with will be

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initiative KEYWORDS * Cellulose Acetate Membrane * Unusual Phenotype * Immunofixation Electrophoresis * Healthy Japanese Adult * American Indian Sample