Phototherapeutic keratectomy for recurrent corneal erosions


Play all audios:

Loading...

ABSTRACT Recurrent corneal erosion may be a difficult disorder to treat, with a number of patients suffering persistent symptoms despite conventional therapy. We present a series of 15


patients (17 eyes) who underwent excimer laser phototherapeutic keratectomy (PTK) for recurrent corneal erosion. In 9 patients a previous episode of corneal trauma could be identified, while


in 6 (8 eyes) the problem had occurred spontaneously. The mean duration of symptoms prior to PTK was 13 months (range 6-60 months). All patients had received lubricant ointments, 7 had


tried bandage contact lenses and 4 had undergone epithelial debridement with no amelioration of their symptoms. The affect area of epithelium was removed and a 20-30 pulse (5-7 µm) ablation


was performed to Bowman's membrane. Great care was taken to avoid the edges of treatment zones from encroaching on the axial cornea. In 11 patients (13 eyes) there was a marked


improvement in symptoms post-operatively with no recurrences. The mean follow-up was 11 months (range 6-24 months). Four patients experienced recurrent episodes 3-6 months after PTK and 2


have subsequently been retreated, 1 of whom has been symptom-free for 12 months. Post-operative best corrected visual acuity was unaltered in 9 eyes and improved by at least one Snellen line


in 8 eyes. Excimer laser PTK appears to be a safe and promising procedure for recurrent corneal erosion in cases refractory to medical treatment. Further studies are indicated to compare


its effectiveness with established surgical procedures. SIMILAR CONTENT BEING VIEWED BY OTHERS SURGICAL OUTCOMES OF RE-EXCIMER LASER PHOTOTHERAPEUTIC KERATECTOMY (RE-PTK) Article Open access


01 June 2021 EFFICACY AND SAFETY OF INTRACORNEAL ALLOGENIC RING SEGMENT IMPLANTATION IN KERATOCONUS: 1-YEAR RESULTS Article 16 June 2023 ALTERATIONS IN THE OCULAR SURFACE AND TEAR FILM


FOLLOWING KERATOPLASTY Article Open access 14 July 2022 ARTICLE PDF REFERENCES * Hansen E . Om den intermitterende keratitis vesiculosa neuralgica af traumatisk oprindsele. _Hospital


Stidende_ 1872; 15: 201–3. Google Scholar  * Bronner A . On some cases of traumatic keratalgia. _Trans Ophthalmol Soc UK_ 1889; 9: 89–94. Google Scholar  * Reuss AV . Ueber recidiverende


traumatische Erosionen der Hornhaut. _Prag Med Wochenschr_ 1898; 21: 243–5. Google Scholar  * Kauffmann E . Klinische Studien zur Frage der rezidivierenden Erosion. _Klin Monastbl


Augenheilkd_ 1907; 45: 202–10. Google Scholar  * Peters A . Ueber traumatische Homhauterkrandungen und ihre Beziehungen zum Herpes Cornea. _Graefes Arch Klin Exp Ophthalmol_ 1904; 57:


93–137. Article  Google Scholar  * Thygeson P . Observations on recurrent erosion of the cornea. _Am J Ophthalmol_ 1959; 47: 48–52. Article  CAS  Google Scholar  * Cogan GD, Donaldson DD,


Kuwabara T, _el al._ Microcystic dystrophy of the corneal epithelium. _Trans Am Ophthalmol Soc_ 1964; 62: 213–5. CAS  PubMed  PubMed Central  Google Scholar  * Kauffman HE, Clower JW .


Irregularities of Bowman's membrane. _Am J Ophthalmol Soc_ 1966; 61: 227–30. Article  Google Scholar  * Goldman JN, Dohlman CH, Kravitt BA . The basement membrane of the human cornea in


recurrent epithelial erosion syndrome. _Trans Am Acad Ophthalmol Otolaryngol_ 1969; 73: 471–81. CAS  PubMed  Google Scholar  * Trobe JD, Laibson PR . Dystrophic changes in the anterior


cornea. _Arch Ophthalmol_ 1972; 87: 378–82. Article  CAS  Google Scholar  * Hykin PG, Foss AE, Pavesio C, Dart JKG . The natural history and management of recurrent corneal erosion: a


prospective randomised trial. _Eye_ 1994; 8: 35–40. Article  Google Scholar  * Hull DS, Hyndiuk RA, Chin GN, et al. Clinial experience with the therapeutic hydrophilic contact lens. _Ann


Ophthalmol_ 1975; 7: 555–62. CAS  PubMed  Google Scholar  * Mobilia EF, Foster CS . The management of recurrent corneal erosions with ultrathin lenses. _Contact Intraocul Lens Med J_ 1978;


4: 25–9. Google Scholar  * Buxton FN, Fox ML . Superficial epithelial keratectomy in the treatment of epithelial basement membrane dystrophy. _Arch Ophthalmol_ 1983; 101: 392–5. Article  CAS


  Google Scholar  * McLean EN, MacRea SM, Rich LE Recurrent erosion: treatment by anterior stromal puncture. _Ophthalmology_ 1986; 93: 784–8. Article  CAS  Google Scholar  * Wood TO .


Recurrent erosion. _Trans Am Ophthalmol Soc_ 1984; 82: 850–98. CAS  PubMed  PubMed Central  Google Scholar  * Wood TO, McLaughlin BJ . Recurrent erosion. _Int Ophthalmol Clin_ 1988; 28:


83–93. Article  CAS  Google Scholar  * Gartry D, Kerr Muir M, Marshall J . Excimer laser treatment of corneal surface pathology: a laboratory and clinical study. _Br J Ophthalmol_ 1991; 75:


258–69. Article  CAS  Google Scholar  * Marshall J, Trokel S, Rothery S, Schubert H . An ultrastructural study of corneal incisions induced by an excimer laser at 193 nm. _Ophthalmology_


1985; 92: 749–58. Article  CAS  Google Scholar  * Marshall J, Trokel S, Rothery S, Krueger RR . A comparative study of corneal incisions induced by diamond and steel knives and two


ultraviolet radiations from an excimer laser. _Br J Ophthalmol_ 1986; 70: 482–501. Article  CAS  Google Scholar  * Puliafito CA, Steinert RF, Deutsch TF, Hillenkamp F, Dehm EJ, Alder CM .


Excimer laser ablation of the cornea and lens: experimental studies. _Ophthalmology_ 1985; 92: 741–8. Article  CAS  Google Scholar  * Marhshall J, Trokel S, Rothery S, Kreuger RR .


Photo-ablative reprofiling of the cornea using an excimer laser: photo refractive keratectomy. _Lasers Ophthalmol_ 1986; 1: 21–8. Google Scholar  * Sher NA, Bowers RA, Zabel RW, Frantz JM,


Eiferman RA, Brown DC, et al. Clinical use of the 193 nm excimer laser in the treatment of corneal scars. _Arch Ophthalmol_ 1991; 109: 491–8. Article  CAS  Google Scholar  * Stark WJ .


Chamon W, Kamp MT, Enger CL, Rencs EV, Gottsh JD. Clinical follow-up of 193 nm ArF excimer laser photokeratectomy. _Ophthalmology_ 1992; 99: 805–12. Article  CAS  Google Scholar  * Fagerholm


P, Fitzsimmons TD, Orndahl M . Ohman L, Tengroth B . Phototherapeutic keratectomy: long-term follow-up results in 166 treated eyes. _Refract Corneal Surg_ 1993; (suppl)9: S76–80. *


O'Brart DPS, Gartry DS, Lohmann CP, Patmore AL, Kerr Muir MG, Marshall J . Treatment of band keratopathy by excimerlaser phototherapeutic keratectomy (PTK): surgical techniques and long


term follow-up. _Br J Ophthalmol_ 1993; 77: 702–8. Article  CAS  Google Scholar  * Steinert RF, Puliafito CA . Excimer laser phototherapeutic keratectomy for a corneal nodule. _Refract


Corneal Surg_ 1990; 6: 352. CAS  PubMed  Google Scholar  * Dausch D, Landesz M, Klein R, Schroder E . Phototherapeutic keratectomy in recurrent corneal epithelial erosion. _Refract Corneal


Surg_ 1993; 9: 419–24. CAS  PubMed  Google Scholar  * Wolff E . Anatomy of the eye and orbit. 6th ed, revised by Last RJ. London: HK Lewis, 1968;36. * Lohmann CP, Gartry D, Kerr Muir M,


Timberlake G, Fitzke F, Marshall J . Haze in photorefractive keratectomy: its origins and consequences. _Laser Light Ophthalmol_ 1991; 4: 15–34. Google Scholar  * O'Brart DPS, Lohmann


CP, Fitzke FE, Klonos G, Corbett MC, Kerr Muir MG, Marshall J . Disturbances in night vision after excimer laser photorefractive keratectomy. _Eye_ 1994;in press. * Geggel J . Successful


treatment of recurrent corneal erosion with Nd:YAG anterior stromal puncture. _Am J Ophthalmol_ 1990; 110: 404–7. Article  CAS  Google Scholar  * Katsev DA, Kincaid MC, Fouraker BD, Dresner


MS, Schanzlin DJ . Recurrent corneal erosion: pathology of corneal puncture. _Cornea_ 1991; 10: 418–23. Article  CAS  Google Scholar  * Garty DS, Kerr Muir MG, Marshall J . Photorefractive


keratectomy with an argon fluoride excimer laser: a clinical study. _Refract Corneal Surg_ 1991; 7: 420–35. Google Scholar  * Seiler T, Holschbach A, Derse M, Jean B, Genth U . Complications


of myopic photorefractive keratectomy with the excimer laser. _Ophthalmology_ 1994; 101: 153–60. Article  CAS  Google Scholar  * SundarRaj N, Geiss M, Fantes F, et al. Healing of excimer


laser ablated monkey corneas: an immunohistochemical evaluation. _Arch Ophthalmol_ 1990; 108: 1604–10. Article  CAS  Google Scholar  * Marshall J, Trokel SL, Rothery S, Krueger RR .


Long-term healing of the central cornea after photorefractive keratectomy using an excimer laser. _Ophthalmology_ 1988; 95: 1411–21. Article  CAS  Google Scholar  Download references AUTHOR


INFORMATION AUTHORS AND AFFILIATIONS * London David P S O'Brart, Malcolm G Kerr Muir & John Marshall Authors * David P S O'Brart View author publications You can also search


for this author inPubMed Google Scholar * Malcolm G Kerr Muir View author publications You can also search for this author inPubMed Google Scholar * John Marshall View author publications


You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE O'Brart, D., Muir, M. & Marshall, J.


Phototherapeutic keratectomy for recurrent corneal erosions. _Eye_ 8, 378–383 (1994). https://doi.org/10.1038/eye.1994.90 Download citation * Issue Date: 01 July 1994 * DOI:


https://doi.org/10.1038/eye.1994.90 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently


available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * Excimer laser * Recurrent erosion