Uveitis presenting de novo in the elderly

ABSTRACT Seventy-one consecutive patients presenting with their first episode of uveitis at the age of 60 or more years, were studied retrospectively. The majority were found to have

idiopathic uveitides on investigation. In those who did have associated systemic disease, the commonest finding was non-insulin-dependent diabetes mellitus or an autoimmune disease. There

were no cases of ocular lymphoma in this series. We conclude that, contrary to some previous reports, idiopathic uveitis may occur in the elderly, and that the relative frequencies of acute

anterior, chronic anterior, intermediate and posterior uveitides are similar to those seen in young patients. SIMILAR CONTENT BEING VIEWED BY OTHERS A DECADE-LONG REVIEW: INSIGHTS INTO

DIAGNOSIS AND DISEASE EVOLUTION OF UVEITIS FROM A SINGLE-CENTER STUDY Article 05 April 2025 ASSOCIATION OF UVEITIS WITH PEDIATRIC AUTOIMMUNE DISEASES BASED ON A TRINETX STUDY Article Open

access 30 December 2024 FUCHS’ UVEITIS SYNDROME: A 20-YEAR EXPERIENCE IN 466 PATIENTS Article Open access 14 April 2024 ARTICLE PDF REFERENCES * Darreil RW, Wagener HP, Kurland LT .

Epidemiology of uveitis. _Arch Ophthalmology_ 1962; 68: 502. Article  Google Scholar  * Mortensen KK, Sjolie AK, Goldschmidt E . Uveitis. _Eine epidemiologische Untersuchung. Ber Dtsch

Ophthalmol Ges_ 1981; 78: 97. Google Scholar  * Ridley ME, McDonald R, Steinberg P Jr, Blumenkranz MS, Zarbin MA, Schachat A . Retinal manifestations of ocular lymphoma (reticulum cell

sarcoma). _Ophthalmology_ 1987; 94: 1631. Article  Google Scholar  * Freeman LN, Schachat AP, Knox DL, et al. Clinical features, laboratory investigations, and survival in ocular reticulum

cell sarcoma. _Ophthalmology_ 1987; 94: 1631. Article  CAS  Google Scholar  * Siegel MJ, Dalton J, Friedman AH, Strauchen J, Watson C . Ten-year experience with primary ocular reticulum cell

sarcoma (large cell non-Hodgkin's lymphoma). _Br J Ophthalmol_ 1989; 73: 342. Article  CAS  Google Scholar  * Vadot E, Barth E, Billet P . Epidemiology of uveitis: preliminary results

of a prospective study in the Savoy. In: Saari KM, editor. Uveitis update. Amsterdam: Excerpta Medica, 1984:13. * Perkins ES . Uveitis and toxoplasmosis. Boston: Little Brown, 1961:9. *

Henderly DE, Genstier AJ, Smith RE, Rao NA . Changing patterns of uveitis. _Am J Ophthalmol_ 1987; 103: 131. Article  CAS  Google Scholar  * Baarsma GS . The epidemiology and genetics of

endogenous uveitis: a review. _Curr Eye Res_ 1992; 11: 1. Article  Google Scholar  * Smith RE, Nozik RA . Uveitis: a clinical approach to diagnosis and management. Baltimore: Williams &

Wilkins, 1990. * Nussenblatt RB, Palestine AG . Uveitis: fundamentals and clinical practice. Chicago: Year Book Medical Publishers, 1989. * James DG . Ocular sarcoidosis. In: Rose EC,

editor. The eye in general medicine. London: Chapman and Hall, 1983. * Rogers RS, Tindall JP . Geriatric herpes zoster. _J Am Geriat Soc_ 1971; 19: 495. Article  Google Scholar  * Secchi AG,

Tognon MS . Systemic disease-related and non-infectious uveitis. _Curr Opin Ophthalmol_ 1991; 2: 480. Google Scholar  * Osborne BM, Butler JJ . Clinical implications of nodal reactive

follicular hyperplasia in the elderly patient with enlarged lymph nodes. _Mod Pathol_ 1991; 4: 24. CAS  PubMed  Google Scholar  * Chavance M, Herberth B, Lesoud B . Delayed-type

hyper-sensitivity and circulating basophils: a population study. _Allergy_ 1991; 46: 401. Article  CAS  Google Scholar  * Rothova A, Meenken C, Michels PJ, Kijlstra A . Uveitis and diabetes

mellitus. _Am J Ophthalmol_ 1988; 106: 17. Article  CAS  Google Scholar  * Falconer DS, Duncan LJP, Smith C . A statistical and gen-etical study of diabetes. I. Prevalence and morbidity.

_Ann Hum Genet_ 1971; 34: 347. Article  CAS  Google Scholar  * Gaasterland D, Kupfer C, Milton R, et al. Effects of age upon parameters of intraocular pressure in normal human eyes. _Exp Eye

Res_ 1978; 26: 651. Article  CAS  Google Scholar  * Hoskins HD Jr, Kass M . Secondary open-angle glaucoma. In: Diagnosis and therapy of the glaucomas. 6th ed. St Louis: Mosby, 1989:332. *

Liesegang TJ . Clinical features and prognosis in Fuchs' uveitis syndrome. _Arch Ophthalmol_ 1982; 100: 1622. Article  CAS  Google Scholar  * Obenauf CD, Shaw HE, Sydnor CF, Klintworth

GK . Sarcoidosis and its ophthalmic manifestations. _Am J Ophthalmol_ 1978; 86: 648. Article  CAS  Google Scholar  * Calabro JJ, Parrino GR, Atchoo PD, et al. Chronic iridocy-clitis in

juvenile rheumatoid arthritis. _Arthritis Rheum_ 1970; 13: 406. Article  CAS  Google Scholar  * Womack LW . Liesegang TJ . Complications of herpes zoster ophthalmicus. _Arch Ophthalmol_

1983; 101: 42. Article  CAS  Google Scholar  * Kim EW, Zakov ZN, Albert DM . Intraocular reticulum cell sarcoma. _Graefes Arch Klin Exp Ophthalmol_ 1979; 209: 167. Article  CAS  Google

Scholar  * Char DH . Intraocular lymphoid lesions. In: Clinical ocular oncology. 1st ed. Edinburgh: Churchill Livingstone, 1989:168. * Holland GN . Discussion: retinal signs in ocular

lymphoma—Ridley _et al_. _Ophthalmology_ 1992; 99: 1160. Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Uveitis Clinic, Moorfields Eye Hospital, London, UK

K Barton, C E Pavesio, H M A Towler & S Lightman Authors * K Barton View author publications You can also search for this author inPubMed Google Scholar * C E Pavesio View author

publications You can also search for this author inPubMed Google Scholar * H M A Towler View author publications You can also search for this author inPubMed Google Scholar * S Lightman View

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Towler, H. _et al._ Uveitis presenting _de novo_ in the elderly. _Eye_ 8, 288–291 (1994). https://doi.org/10.1038/eye.1994.59 Download citation * Issue Date: 01 May 1994 * DOI:

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available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * Age factors * Autoimmunity * Human * Systemic disease * Uveitis