Serum levels of folate, lycopene, β-carotene, retinol and vitamin e and prostate cancer risk

ABSTRACT Previous studies relating increased serum levels of folate and fat-soluble vitamins to prostate cancer risk have variously shown null associations or to either decrease or increase

the risk of developing prostate cancer. Prospective studies of serum folate levels have been reported to show a null association and increased serum levels to either decrease or increase the

risk of subsequently developing prostate cancer. Similarly, serum β-carotene and lycopene levels have either been reported to be inversely correlated or not associated with prostate cancer

risk. Using a prospective nested case-control study design, which minimized the possibility of disease effects on serum-vitamin concentrations, we report null associations for serum

concentrations of folate, lycopene, β-carotene, vitamin A and vitamin E, and subsequent development of prostate cancer. Access through your institution Buy or subscribe This is a preview of

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Biochemistry Section, PathWest, Queen Elizabeth II Medical Centre, Nedlands, WA, Australia J Beilby & E Rossi * School of Population Health, University of Western Australia, Nedlands,

WA, Australia G L Ambrosini & A W Musk * Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Nedlands, WA, Australia N H

de Klerk * Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia A W Musk Authors * J Beilby View author publications You can also search for this author

inPubMed Google Scholar * G L Ambrosini View author publications You can also search for this author inPubMed Google Scholar * E Rossi View author publications You can also search for this

author inPubMed Google Scholar * N H de Klerk View author publications You can also search for this author inPubMed Google Scholar * A W Musk View author publications You can also search for

this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to E Rossi. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no conflict of interest. RIGHTS AND

PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Beilby, J., Ambrosini, G., Rossi, E. _et al._ Serum levels of folate, lycopene, β-carotene, retinol and vitamin E

and prostate cancer risk. _Eur J Clin Nutr_ 64, 1235–1238 (2010). https://doi.org/10.1038/ejcn.2010.124 Download citation * Received: 27 December 2009 * Revised: 31 March 2010 * Accepted: 08

June 2010 * Published: 04 August 2010 * Issue Date: October 2010 * DOI: https://doi.org/10.1038/ejcn.2010.124 SHARE THIS ARTICLE Anyone you share the following link with will be able to

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initiative KEYWORDS * folate * lycopene * β-carotene * retinol * vitamin E * prostate cancer