Toxicity and costs of cancer treatment reduced by deferring cdk4/6 inhibitor use

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* CLINICAL BRIEFINGS * 27 November 2024 The SONIA study shows that early use of inhibitors that target both CDK4 and CDK6 (hereafter, CDK4/6) in metastatic breast cancer prolongs time on


treatment but does not improve patient outcomes. Postponing innovative treatments to a later stage of the disease could thus safely reduce the time on treatment, the number of adverse


effects for people with breast cancer and the burden on health-care resources.