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Access through your institution Buy or subscribe 50 YEARS AGO Although the annual figures for carriage-rates of all pathogenic staphylococci follow no particular course, evidence from many


sources in industrialized countries shows that this is not the case with regard to the proportions of penicillin-resistant organisms ... These findings raise many questions about the origin


and spread of resistant strains. They are certainly consistent with the general impression of a relationship between the increased use of penicillin and the growth of resistant strains ...


It has to be borne in mind that penicillin, with other antibiotics, is being used on a large scale for preserving food and controlling animal diseases in many countries. It is increasingly


present in milk and cheese, and quite large numbers of hospital, veterinary and farm workers are intermittently or continuously exposed to small concentrations of the antibiotic. These are


all factors likely to promote the emergence of resistant strains in man. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution


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Contact customer support RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE 50 & 100 years ago. _Nature_ 482, 479 (2012).


https://doi.org/10.1038/482479a Download citation * Published: 22 February 2012 * Issue Date: 23 February 2012 * DOI: https://doi.org/10.1038/482479a SHARE THIS ARTICLE Anyone you share the


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