Ionic radius selectivity of skeletal muscle membranes


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ABSTRACT THERE have been several reports1–3 that the trivalent lanthanide cations bind to sites on membranes that are normally occupied by Ca2+. In skeletal muscle, Ca2+ is important for the


functions of both the outer sarcolemma4 and the internal sarcoplasmic reticulum5,6. Here I report the inhibitory effects of 13 lanthanide ions on these Ca2+-mediated functions. The


relationship between ionic radius and the degree of inhibition is different in these two membranes. There are features of the data which are difficult to explain by assuming that charge


density alone determines cation recognition at the membrane surface. But it would also be too simplistic to suggest that the lanthanide ions are selected only on the basis of ionic radius.


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ORTHOPHOSPHATE INCREASES THE EFFICIENCY OF SLOW MUSCLE-MYOSIN ISOFORM IN THE PRESENCE OF OMECAMTIV MECARBIL Article Open access 07 July 2020 REFERENCES * Mela, L. _Biochemistry_ 8, 2481–2486


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AUTHORS AND AFFILIATIONS * Muscle Research Unit, Department of Anatomy, The University of Sydney, Sydney, NSW, 2006, Australia C. G. DOS REMEDIOS Authors * C. G. DOS REMEDIOS View author


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selectivity of skeletal muscle membranes. _Nature_ 270, 750–751 (1977). https://doi.org/10.1038/270750a0 Download citation * Received: 01 September 1977 * Accepted: 28 October 1977 *


Published: 01 December 1977 * Issue Date: 22 December 1977 * DOI: https://doi.org/10.1038/270750a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this


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