Β-endorphin in vitro inhibition of striatal dopamine release

ABSTRACT THERE has been considerable recent interest in endogenous peptides as possible analgesic agents since the isolation of a pentapeptide with opiate-like activity

(methionine-enkephalin) from porcine brain1. Of particular interest is _β_-endorphin, isolated from camel pituitary glands2, and now synthesised3. We report here the inhibitory effect _in

vitro_ of _β_-endorphin on striatal dopamine release from the central nervous system (CNS). Access through your institution Buy or subscribe This is a preview of subscription content, access

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references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pharmacology, University of California, San Francisco, California, 94143 HORACE H. LOH, DAVID A. BRASE, SUMATHY

SAMPATH-KHANNA, JEFFREY B. MAR & E. LEONG WAY * Hormone Research Laboratory, University of California, San Francisco, California, 94143 CHOH HAO LI Authors * HORACE H. LOH View author

publications You can also search for this author inPubMed Google Scholar * DAVID A. BRASE View author publications You can also search for this author inPubMed Google Scholar * SUMATHY

SAMPATH-KHANNA View author publications You can also search for this author inPubMed Google Scholar * JEFFREY B. MAR View author publications You can also search for this author inPubMed 

Google Scholar * E. LEONG WAY View author publications You can also search for this author inPubMed Google Scholar * CHOH HAO LI View author publications You can also search for this author

inPubMed Google Scholar ADDITIONAL INFORMATION The erratum article can be found online at https://doi.org/10.1038/267290b0 RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE

CITE THIS ARTICLE LOH, H., BRASE, D., SAMPATH-KHANNA, S. _et al._ β-Endorphin _in vitro_ inhibition of striatal dopamine release. _Nature_ 264, 567–568 (1976).

https://doi.org/10.1038/264567a0 Download citation * Received: 05 August 1976 * Accepted: 28 September 1976 * Published: 01 December 1976 * Issue Date: 09 December 1976 * DOI:

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