Evidence for dopamine receptors mediating sedation in the mouse brain

ABSTRACT APOMORPHINE, a direct stimulant of dopamine (DA) receptors, and L-dopa, the direct precursor of DA, have a biphasic action on behaviour; in low doses they decrease motor activity,

while in higher doses they cause hyper-motility and sterotypy1–3. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution

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about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS DIAZEPAM CAUSES SEDATIVE RATHER THAN ANXIOLYTIC EFFECTS IN C57BL/6J MICE

Article Open access 29 April 2021 DOPAMINE D1-LIKE RECEPTOR BLOCKADE AND STIMULATION DECREASES OPERANT RESPONDING FOR NICOTINE AND FOOD IN MALE AND FEMALE RATS Article Open access 19 August

2022 THE DOPAMINERGIC EFFECTS OF ESKETAMINE ARE MEDIATED BY A DUAL MECHANISM INVOLVING GLUTAMATE AND OPIOID RECEPTORS Article Open access 19 February 2025 REFERENCES * Strömberg, U., and

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AUTHORS AND AFFILIATIONS * Institute of Pharmacology, University of Cagliari, Via Porcell, 4, 09100, Cagliari, Italy G. DI CHIARA, M. L. PORCEDDU, L. VARGIU, A. ARGIOLAS & G. L. GESSA

Authors * G. DI CHIARA View author publications You can also search for this author inPubMed Google Scholar * M. L. PORCEDDU View author publications You can also search for this author

inPubMed Google Scholar * L. VARGIU View author publications You can also search for this author inPubMed Google Scholar * A. ARGIOLAS View author publications You can also search for this

author inPubMed Google Scholar * G. L. GESSA View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS

ARTICLE CITE THIS ARTICLE DI CHIARA, G., PORCEDDU, M., VARGIU, L. _et al._ Evidence for dopamine receptors mediating sedation in the mouse brain. _Nature_ 264, 564–567 (1976).

https://doi.org/10.1038/264564a0 Download citation * Received: 20 July 1976 * Accepted: 07 October 1976 * Published: 01 December 1976 * Issue Date: 09 December 1976 * DOI:

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