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ABSTRACT The mechanism of action of the plant toxins abrin and ricin is described. The toxins inhibit protein synthesis probably by inactivating the 60S ribosomal subunits, interfering with
chain elongation. Only eukaryotic ribosomes are attacked by the toxins. Access through your institution Buy or subscribe This is a preview of subscription content, access via your
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* Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS POST TRANSLATIONAL MODIFICATIONS OF TRIFOLITOXIN: A BLUE
FLUORESCENT PEPTIDE ANTIBIOTIC Article Open access 12 January 2022 ANTIVIRAL ACTIVITY OF BACTERIAL TIR DOMAINS VIA IMMUNE SIGNALLING MOLECULES Article 01 December 2021 NOD-LIKE
RECEPTOR-MEDIATED PLANT IMMUNITY: FROM STRUCTURE TO CELL DEATH Article 08 December 2020 REFERENCES * Olsnes, S., _Naturwissenschaften_, 59, 497 (1972). Article ADS CAS Google Scholar *
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Hydro's Institute for Cancer Research, Montebello, Oslo, 3, Norway Sjur Olsnes, Karin Refsnes & Alexander Pihl Authors * Sjur Olsnes View author publications You can also search for
this author inPubMed Google Scholar * Karin Refsnes View author publications You can also search for this author inPubMed Google Scholar * Alexander Pihl View author publications You can
also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Olsnes, S., Refsnes, K. & Pihl, A. Mechanism of
action of the toxic lectins abrin and ricin. _Nature_ 249, 627–631 (1974). https://doi.org/10.1038/249627a0 Download citation * Received: 20 December 1973 * Revised: 11 February 1974 * Issue
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