Pattern of remyelination in the cns

ABSTRACT IT has been suggested that reduction of internodal length may be a feature of remyelinated central nerve fibres as it is of peripheral nerve fibres1. As the technique for measuring

internodal length of nerve fibres in the central nervous system (CNS) is tedious and requires a high degree of skill and patience from the investigator2, it is unlikely that this method can

be applied to routine neuropathological investigations. Recent ultrastructural studies on remyelination in the mouse, following primary demyelination induced by feeding cuprizone (Bis -

cyclohexanone - oxaldihyrozone)3–5 have shown that measurements of the relationship between myelin sheath thickness and axon diameter provides an easier method of identifying remyelinated

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support SIMILAR CONTENT BEING VIEWED BY OTHERS FILTERING PROPERTY OF MYELINATED INTERNODE CAN CHANGE NEURAL INFORMATION REPRESENTABILITY AND MIGHT TRIGGER A COMPENSATORY ACTION DURING

DEMYELINATION Article Open access 14 December 2023 REMYELINATION PROTECTS NEURONS FROM DLK-MEDIATED NEURODEGENERATION Article Open access 23 October 2024 MYELIN REPLACEMENT TRIGGERED BY

SINGLE-CELL DEMYELINATION IN MOUSE CORTEX Article Open access 29 September 2020 REFERENCES * Gledhill, R. F., Harrison, B. M., and McDonald, W. I., _Nature_, 244, 433 (1973). Article  ADS 

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Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Wellcome Laboratory for Comparative Neurology, School of Veterinary Medicine, Cambridge, UK W. F. BLAKEMORE

Authors * W. F. BLAKEMORE View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS

ARTICLE BLAKEMORE, W. Pattern of remyelination in the CNS. _Nature_ 249, 577–578 (1974). https://doi.org/10.1038/249577a0 Download citation * Received: 11 February 1974 * Revised: 11 March

1974 * Issue Date: 07 June 1974 * DOI: https://doi.org/10.1038/249577a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link

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