Gangliosides as membrane receptors for tetanus toxin, cholera toxin and serotonin


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Tetanus toxin is bound by a sialidase-labile disialosyl ganglioside, serotonin by another, and cholera toxin by a sialidase-stable monosialosyl ganglioside. There is good evidence that the


monosialosyl ganglioside may be the receptor for cholera toxin in cell membranes; what of the disialosyl ganglioside and tetanus toxin?


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