Aggregation of protein particles in tumour cells


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ABSTRACT IN the cytoplasm of the cells of some tumours (Ehrlich ascites tumour, Yoshida ascites tumour, Walker carcinoma, hepatoma of the rat and human malignant lymphogranuloma) a form of


dispersion of the ribosomes has been seen1–3 at the electron microscope described4–6 as ‘scattered’ or ‘unorganized ergastoplasm’. A similar condition also occurs3,7 during the


previtellogenesis of the oocytes in some animal species (_Haliotis lamellosa_, _Paracentrotus lividus_, _Sphaerechinus granularis_, _Arbacia lixula_). While in tumour cells ‘scattered


ergastoplasm’ persists, it is seen8 that in the oocytes the ribosomes, after having increased and probably having undergone a transformation, aggregate during vitellogenesis to make yolk


globules (Figs. 1 and 4). Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your


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Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Istituto di Zoologia e di Anatomia comparata, Università di Messina, A. BOLOGNARI Authors * A.


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BOLOGNARI, A. Aggregation of Protein Particles in Tumour Cells. _Nature_ 190, 358–359 (1961). https://doi.org/10.1038/190358a0 Download citation * Issue Date: 22 April 1961 * DOI:


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