Laryngeal stenosis associated with chronic graft-versus-host disease following unrelated bone marrow transplantation

Access through your institution Buy or subscribe Obstructive and restrictive pulmonary diseases are clinical manifestations of chronic graft-versus-host disease (GVHD) in the airway tract,

and involvement of the upper respiratory tract is unusual. We present a case of glottic and subglottic stenosis that presented with extensive chronic GVHD. Laryngotracheal stenosis may be

congenital or acquired, and the type of stenosis is classified into supraglottic, glottic, or subglottic stenosis based on the anatomic location. Acquired glottic and subglottic stenosis

most commonly results from trauma secondary to endotracheal intubation.1, 2 Other causes include inflammation, infection and trauma and rarely neoplasms. The present patient had never been

intubated. Rarely, glottic stenosis caused by granulomatous infections or inflammatory diseases including tuberculosis, sarcoidosis and Wegener's granulomatosis has been reported.3, 4

This patient had no history of symptoms, signs or evidence suggesting the presence of these diseases. This is a preview of subscription content, access via your institution ACCESS OPTIONS

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institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * McCaffrey TV . Classification of laryngotracheal stenosis. _Laryngoscope_ 1992; 102: 1335–1340. Article 

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1341–1345. Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Division of Hematology and Oncology, Department of Medicine, Akita University

School of Medicine, Akita, Japan M Hirokawa, M Kume & K-i Sawada * Department of Otolaryngology, Akita University School of Medicine, Akita, Japan T Wu & K Ishikawa Authors * M

Hirokawa View author publications You can also search for this author inPubMed Google Scholar * M Kume View author publications You can also search for this author inPubMed Google Scholar *

T Wu View author publications You can also search for this author inPubMed Google Scholar * K Ishikawa View author publications You can also search for this author inPubMed Google Scholar *

K-i Sawada View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Hirokawa,

M., Kume, M., Wu, T. _et al._ Laryngeal stenosis associated with chronic graft-versus-host disease following unrelated bone marrow transplantation. _Bone Marrow Transplant_ 38, 387–388

(2006). https://doi.org/10.1038/sj.bmt.1705451 Download citation * Published: 24 July 2006 * Issue Date: 01 September 2006 * DOI: https://doi.org/10.1038/sj.bmt.1705451 SHARE THIS ARTICLE

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