Fournier’s gangrene: a clinical presentation of necrotizing fasciitis after bone marrow transplantation

ABSTRACT Three patients with ANLL developed Fournier’s gangrene as an early complication after allo-BMT (two cases) and auto-BMT (one case); two patients were in first CR, the third had

resistant disease. Patients developed fever, perineal pain, swelling and blistering of the genital area. _Pseudomonas aeruginosa_ was isolated from the lesions and patients received systemic

antibiotic therapy, surgical debridement and medication with potassium permanganate solution. Two patients made a complete recovery although one died of sepsis. The third had progressive

involvement of the abdominal wall and later died of leukemia. Early diagnosis of this disorder and prompt initiation of appropriate therapy can prevent progression of this acute necrotizing

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REPORTS WITH _RIT1_ VARIANTS AND LITERATURE REVIEW Article Open access 04 June 2025 AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Centro Trapianti di Midollo Osseo, Istituto di Ematologia,

IRCCS Policlinico S Matteo, Pavia, Italy G Martinelli, EP Alessandrino, P Bernasconi, D Caldera, A Colombo, L Malcovati & C Bernasconi * Clinica Dermatologica, IRCCS Policlinico S

Matteo, Pavia, Italy MR Gaviglio, GP Vignoli & G Borroni Authors * G Martinelli View author publications You can also search for this author inPubMed Google Scholar * EP Alessandrino

View author publications You can also search for this author inPubMed Google Scholar * P Bernasconi View author publications You can also search for this author inPubMed Google Scholar * D

Caldera View author publications You can also search for this author inPubMed Google Scholar * A Colombo View author publications You can also search for this author inPubMed Google Scholar

* L Malcovati View author publications You can also search for this author inPubMed Google Scholar * MR Gaviglio View author publications You can also search for this author inPubMed Google

Scholar * GP Vignoli View author publications You can also search for this author inPubMed Google Scholar * G Borroni View author publications You can also search for this author inPubMed 

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THIS ARTICLE Martinelli, G., Alessandrino, E., Bernasconi, P. _et al._ Fournier’s gangrene: a clinical presentation of necrotizing fasciitis after bone marrow transplantation. _Bone Marrow

Transplant_ 22, 1023–1026 (1998). https://doi.org/10.1038/sj.bmt.1701438 Download citation * Received: 18 February 1998 * Accepted: 20 June 1998 * Published: 20 November 1998 * Issue Date:

01 November 1998 * DOI: https://doi.org/10.1038/sj.bmt.1701438 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a

shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * Fournier’s gangrene * necrotizing

fasciitis * bone marrow transplantation