Cross-linkage formation in keratin

ABSTRACT WHEN animal fibres, such as wool and hair, are treated with an acid solution of 3 : 4-_iso_propylidene 1 : 2-5 : 6-dianhydromannitol for 24 hr. at 50° C., cross-linkages are formed

between the carboxyl groups of neighbouring peptide chains1. Since the fibres are then more resistant to deformation, their felting power is reduced, and attention has therefore been turned

to the possibility of cross-linking wool with simpler di-epoxides, for example, 1 : 2-3 : 4-diepoxybutane (I) and 1 : 2-5 : 6-diepoxyhexane (II). For this purpose, Lincoln wool fibres were

purified by extraction with alcohol and ether, washed in distilled water, and then treated for 24 hr. at 50° C. with a 2.5 per cent solution of the di-epoxide in a phosphate buffer at the

appropriate _p_H. After being washed in running water for 24 hr., the fibres were examined for the presence of new cross-linkages by determining the extent to which supercontraction could be

induced by boiling for 30 min. in a 5 percent solution of sodium metabisulphite2. The results are given in the accompanying table. Access through your institution Buy or subscribe This is a

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MAMMALIAN COLLAGENS I AND III WITHIN ANCIENT PORIFERAN BIOPOLYMER SPONGIN Article Open access 13 March 2025 SELF-ASSEMBLY OF A LAYERED TWO-DIMENSIONAL MOLECULARLY WOVEN FABRIC Article 16

December 2020 IDENTIFICATION, DETERIORATION, AND PROTECTION OF ORGANIC CULTURAL HERITAGES FROM A MODERN PERSPECTIVE Article Open access 11 March 2025 REFERENCES * Capp and Speakman, _J. Soc.

Dyers and Colourists_, 65, 402 (1949). Article  CAS  Google Scholar  * Speakman, _J. Soc. Dyers and Colourists_, 52, 335 (1936); _J. Text. Inst._, 38, T102 (1947). Article  CAS  Google

Scholar  * Wiggins and Wood, _Nature_, 164, 402 (1949). Article  ADS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Textile Chemistry Laboratory,

Department of Textile Industries, University, Leeds, 2 C. FEARNLEY & J. B. SPEAKMAN Authors * C. FEARNLEY View author publications You can also search for this author inPubMed Google

Scholar * J. B. SPEAKMAN View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS

ARTICLE FEARNLEY, C., SPEAKMAN, J. Cross-Linkage Formation in Keratin. _Nature_ 166, 743–744 (1950). https://doi.org/10.1038/166743a0 Download citation * Issue Date: 28 October 1950 * DOI:

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