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ABSTRACT THERE are at present two groups of enzymes in mammals which hydrolyse acetylcholine: the first hydrolyses acetylcholine and acetyl-β-methylcholine and is found primarily in nervous
tissue and red blood cells; the second group hydrolyses acetylcholine and benzoylcholine and is found in the serum and tissues of some animal species. Characteristic of this last group is
the enzyme in human serum. In addition, there is one other related enzyme or group of enzymes which hydrolyses benzoylcholine but not acetylcholine. This was first noted and labelled
benzoylcholinesterase by Sawyer1, and was reported by us as occurring in rabbit serum2. SIMILAR CONTENT BEING VIEWED BY OTHERS CHOLINESTERASE ACTIVITY IN SERUM DURING GENERAL ANESTHESIA IN
PATIENTS WITH OR WITHOUT VASCULAR DISEASE Article Open access 17 August 2021 OPTIMISATION OF ACID HYDROLYSIS CONDITIONS OF CHOLINE ESTERS AND MASS SPECTROMETRIC DETERMINATION OF TOTAL
CHOLINE IN VARIOUS FOODS Article Open access 02 August 2024 CELLULAR AND ORGANISMAL FUNCTION OF CHOLINE METABOLISM Article 08 January 2025 ARTICLE PDF REFERENCES * Sawyer, C. H., _Science_,
101, 385 (1945). Article ADS CAS Google Scholar * Levine, M. G., Hoyt, R. E., and Suran, A. A., _Proc. Soc. Exp. Biol. and Med._, 73, 100 (1950). Article CAS Google Scholar Download
references AUTHOR INFORMATION Author notes * MILTON GJELHAUG LEVINE Present address: Kabat-Kaiser Institute, Vallejo, California AUTHORS AND AFFILIATIONS * Institute of Experimental
Medicine, White Memorial Hospital, Los Angeles, 33, California MILTON GJELHAUG LEVINE & ANITA A. SURAN Authors * MILTON GJELHAUG LEVINE View author publications You can also search for
this author inPubMed Google Scholar * ANITA A. SURAN View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions
ABOUT THIS ARTICLE CITE THIS ARTICLE LEVINE, M., SURAN, A. A New Cholinesterase in Swine Serum. _Nature_ 166, 698 (1950). https://doi.org/10.1038/166698a0 Download citation * Issue Date: 21
October 1950 * DOI: https://doi.org/10.1038/166698a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link
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