Vitamin b12 and antihistamine activity


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ABSTRACT TRAINA1 has reported that intraperitoneal injections of vitamin B12 prevent histamine shock following the intracardiac administration of histamine to guinea pigs. Antagonism between


histamine and vitamin B12 might be of importance in the assay of histamine in liver extracts, and we accordingly investigated this relationship. We have tried to repeat Traina's work,


and have also studied the effect of prior administration of vitamin B12 on the reduction of arterial blood pressure in the cat after intravenous injection of histamine. Access through your


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REFERENCES * Traina, V., _Nature_, 165, 439 (1950). Article  ADS  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Research and Development Division,


Glaxo Laboratories, Limited, Greenford, Middlesex H. M. SHARPE, E. A. WOOLLETT & M. F. J. CUTHBERTSON Authors * H. M. SHARPE View author publications You can also search for this author


inPubMed Google Scholar * E. A. WOOLLETT View author publications You can also search for this author inPubMed Google Scholar * M. F. J. CUTHBERTSON View author publications You can also


search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE SHARPE, H., WOOLLETT, E. & CUTHBERTSON, M. Vitamin B12


and Antihistamine Activity. _Nature_ 166, 651–652 (1950). https://doi.org/10.1038/166651a0 Download citation * Issue Date: 14 October 1950 * DOI: https://doi.org/10.1038/166651a0 SHARE THIS


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