Additional transaminations by insoluble particle preparations of rat liver

ABSTRACT Braunstein and Kritzmann1 suggested that transamination in pigeon breast muscle was a general reaction involving most of the amino-acids; Cohen2 was unable to confirm these results,

and pointed out the lack of experimental controls. Further work by Cohen3 with purified enzyme preparations suggested that the transamination reactions were limited to L-glutamate +

oxalacetate ⇌ α-ketoglutarate + L-aspartate and L-glutamate + pyruvate ⇌ α-ketoglutarate + L-alanine. Slower but significant reactions with other amino-acids have been shown to occur in

kidney and liver homogenates by the same author4. Various workers5–8 minimized these findings when assessing the general significance of transamination reactions. Access through your

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BEING VIEWED BY OTHERS A WAY TO THIOACETATE ESTERS COMPATIBLE WITH NON-OXIDATIVE PREBIOTIC CONDITIONS Article Open access 02 September 2020 SPONTANEOUS HYDROLYSIS AND SPURIOUS METABOLIC

PROPERTIES OF Α-KETOGLUTARATE ESTERS Article Open access 12 August 2021 TRACING THE LACTATE SHUTTLE TO THE MITOCHONDRIAL RETICULUM Article Open access 08 September 2022 REFERENCES *

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Author notes * F. J. R. HIRD: Sir John and Lady Higgins research scholar, Melbourne. AUTHORS AND AFFILIATIONS * Biochemical Laboratory, Cambridge F. J. R. HIRD & E. V. ROWSELL Authors *

F. J. R. HIRD View author publications You can also search for this author inPubMed Google Scholar * E. V. ROWSELL View author publications You can also search for this author inPubMed 

Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE HIRD, F., ROWSELL, E. Additional Transaminations by Insoluble Particle Preparations of Rat

Liver. _Nature_ 166, 517–518 (1950). https://doi.org/10.1038/166517a0 Download citation * Issue Date: 23 September 1950 * DOI: https://doi.org/10.1038/166517a0 SHARE THIS ARTICLE Anyone you

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