Inhibition of rh agglutination by disodium hydrogen citrate


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ABSTRACT IT was found that _Rh_-positive (that is, _D_-positive) red blood cells suspended in an anti-coagulant preservative solution (2 per cent disodium hydrogen citrate or 'acid


citra'; 2·5 per cent dextrose) were not agglutinated by anti-_D_) grouping sera. Investigating this inhibition, 2 per cent _D_-positive cell suspensions were titrated with a strong


anti-_D_) serum. The titre of cells in isotonic (0·85 per cent) saline and in isotonic (5 per cent) dextrose was 320, but in isotonic mixtures of acid citrate and sodium chloride or dextrose


the titre was reduced according to the acid citrate concentration. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution


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INFORMATION AUTHORS AND AFFILIATIONS * Salisbury Area Pathological Service, General Infirmary, Salisbury J. G. SELWYN Authors * J. G. SELWYN View author publications You can also search for


this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE SELWYN, J. Inhibition of Rh Agglutination by Disodium Hydrogen


Citrate. _Nature_ 164, 493–494 (1949). https://doi.org/10.1038/164493b0 Download citation * Issue Date: 17 September 1949 * DOI: https://doi.org/10.1038/164493b0 SHARE THIS ARTICLE Anyone


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