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ABSTRACT When studying the effects of coagulation lesions caused by high-frequency alternating current passing through electrodes in the brain of monkeys, we often noticed that the injury
was not confined to the needle tip, but extended along the needle. This additional damage was caused by gas bubbles arising from the point of coagulation from the high temperature of the
needle, even when the current was passed for only 10 sec., and from the irregular distribution of the current. The use of direct current often avoids this trouble but has other
disadvantages. To avoid the use of electrodes altogether we found the following purely mechanical cutting instrument useful. Access through your institution Buy or subscribe This is a
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ABLATION WITH TUNABLE LESION SIZE REVEALS MULTIPLE ORIGINS OF SEIZURE-LIKE CONVULSIONS IN _CAENORHABDITIS ELEGANS_ Article Open access 03 March 2021 TRANSCRANIAL FOCUSED ULTRASOUND MODULATES
CORTICAL AND THALAMIC MOTOR ACTIVITY IN AWAKE SHEEP Article Open access 29 September 2021 APPLICATIONS OF FOCUSED ULTRASOUND IN THE BRAIN: FROM THERMOABLATION TO DRUG DELIVERY Article 26
October 2020 AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Physiology, Oxford P. GLEES, P. D. WALL & T. A. WRIGHT Authors * P. GLEES View author publications You can also
search for this author inPubMed Google Scholar * P. D. WALL View author publications You can also search for this author inPubMed Google Scholar * T. A. WRIGHT View author publications You
can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE GLEES, P., WALL, P. & WRIGHT, T. An
Ensheathèd Rotating Knife for Causing Brain Lesions. _Nature_ 160, 365–366 (1947). https://doi.org/10.1038/160365a0 Download citation * Issue Date: 13 September 1947 * DOI:
https://doi.org/10.1038/160365a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently
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